Search Book Here:

Dekker Encyclopedia of Nanoscience and Nanotechnology - 5 Volume Set

Placing specialists at the forefront of the nanoscience revolution, this reference identifies current challenges and development paths sure to influence fields ranging from materials and surface science, chemistry, and biomedicine to computer technology, information processing, and mechanical, optical, and electrical engineering-examining the design, application, and utilization of devices, techniques, and technologies critical to research at atomic, molecular, and macromolecular levels ranging from 1-100 nanometers.

Download Link:

Facility Design and Management Handbook

A new paradigm in facility management-a unique, just-in-time resource from profession leader Eric Teicholz, Facility Design and Management Handbook empowers you to make your facility state of the art. Packed with tips from U.S. and international case studies from government, health care, retail, finance, manufacturing, and academia, this guide gives you access to the productivity tools, technologies, and stratagems that have revolutionized the field in the last five years, helping you to:

Find the best, most cost-effective solutions for issues from “greenness” and sustainability to disaster recovery and technology integration Use new tools for space and asset allocation, project management, process coordination, and systems integration Improve accuracy in financial forecasting, budgeting, architectural and interior design planning, and market research Create cost-effective “smart” buildings with state-of-the art security, energy management, lighting strategies, and maintenance efficiency Discover innovative solutions for human resources needs
Integrate the Internet into your management program Automate nearly all your tasks for major productivity gains Apply benchmarking standards and other measurements that demonstrate and assure facility management productivity

Clean Technology for the Manufacture of Specialty Chemicals

Producing large quantities of waste is not only environmentally unacceptable, it is also not viable in economic terms. The chemical industry, particularly the speciality and pharmaceuticals sectors, is becoming increasingly aware of the advantages associated with clean technology, particularly in terms of competitive advantage and environmental benefits.||Bringing together an understanding of the concepts and values of clean technology by using case studies from some leading European countries, this book provides an insight into subjects such as catalysis; process intensification; and how to measure the "green" value of a process. It also highlights the role played by both the chemical and chemical engineering disciplines in the development of cleaner processes.||Clean Technology for the Manufacture of Speciality Chemicals will prove valuable reading for process development chemists and engineers, particularly those in the specialities and pharmaceuticals sectors, and will also be an important source of teaching material for the growing number of clean technology chemistry courses.

Download [Updated]

Understanding the Benefits and Risks of Pharmaceuticals

Download Link:

Use of non-specific and specific interactions in the analysis of testosterone and related compounds by capillary electromigration techniques

Determination of testosterone and related compounds in body fluids is of utmost importance in doping control and the diagnosis of many diseases. Capillary electromigration techniques are a relatively new approach for steroid research. Owing to their electrical neutrality, however, separation of steroids by capillary electromigration techniques requires the use of charged electrolyte additives that interact with the steroids either specifically or non-specifically. The analysis of testosterone and related steroids by non-specific micellar electrokinetic chromatography (MEKC) was investigated in this study. The partial filling (PF) technique was employed, being suitable for detection by both ultraviolet spectrophotometry (UV) and electrospray ionization mass spectrometry (ESI-MS). Efficient, quantitative PF-MEKCUV methods for steroid standards were developed through the use of optimized pseudostationary phases comprising surfactants and cyclodextrins. PF-MEKCUV proved to be a more sensitive, efficient and repeatable method for the steroids than PF-MEKCESI-MS. We discovered that in PF-MEKC analyses of electrically neutral steroids, ESI-MS interfacing sets significant limitations not only on the chemistry affecting the ionization and detection processes, but also on the separation. The new PF-MEKCUV method was successfully employed in the determination of testosterone in male urine samples after microscale immunoaffinity solid-phase extraction (IA-SPE). The IA-SPE method, relying on specific interactions between testosterone and a recombinant anti-testosterone Fab fragment, is the first such method described for testosterone. Finally, new data for interactions between steroids and human and bovine serum albumins were obtained through the use of affinity capillary electrophoresis. A new algorithm for the calculation of association constants between proteins and neutral ligands is introduced.

Download Link:


Presenting practical approaches to complex formulation problems, this outstanding reference provides a thorough overview of particulate delivery systems-emphasizing specific preparation, characterization, and evaluation methods, as well as potential applications in areas such as pharmacy, medicine, cosmetology, and agriculture.

Download Link:

Handbook of Modern Pharmaceutical Analysis

This book describes the role modern pharmaceutical analysis plays in the development of new drugs. Detailed information is provided as to how the quality of drug products is assured from the point of discovery until the patient uses the drug. Coverage includes state-of-the-art topics such as analytics for combinatorial chemistry and high-throughput screening, formulation development, stability studies, international regulatory aspects and documentation, and future technologies that are likely to impact the field. Emphasis is placed on current, easy-to-follow methods that readers can apply in their laboratories.

No book has effectively replaced the very popular text, Pharmaceutical Analysis, that was edited in the 1960s by Tak Higuchi. This book will fill that gap with an up-to-date treatment that is both handy and authoritative.


Antimicrobial Susceptibility Testing Protocols

The reported increase in the occurrence of antibiotic-resistant bacteria serves to emphasize the importance of accurate susceptibility testing. This timely guide examines the role of the clinical microbiology lab in integrated patient care. The first section addresses basic susceptibility disciplines such as macro and microbroth dilution, agar dilution, and disk diffusion. The second section considers specialized susceptibility protocols that may be performed by a subset of labs, and emphasizes reproducible results. The third section covers antibiotic development and discusses antibiogram design and use. It includes extensive references and a table of antibiotic classes and common bug-drug susceptibilities.

Download Link:

Advances in Pharmaceutical Sciences

The seventh volume of Advances in Pharmaceutical Sciences heralds a welcome continuation of this well-respected series. Acknowledged experts provide comprehensive statements of current research and development in selected fields of pharmaceutical technology. This book will be of great value to those working in academia and the pharmaceutical industry.


Handbook of Drug Screening

A presentation of screening techniques, modern technologies, and high-capacity instrumentation for increased productivity in the development and discovery of new drugs, chemical compounds, and targeted delivery of pharmaceuticals. It contains practical applications and examples of strategies in cell-based and cell-free screens as well as homogeneous, fluorescence, chemiluminescence, and radioactive-based technologies.

Download Link:

Pharmaceutical Process Scale-Up

Focusing on scientific and practical aspects of process scale-up, this resource details the theory and practice of transferring pharmaceutical processes from laboratory scale to the pilot plant and production scale. It covers parenteral and nonparenterel liquids and semi-solids, products derived from biotechnology, dry blending and powder handling, granulation and drying, fluid bed applications, compaction and tableting, and film coating and regulatory requirements for scale-up and postapproval changes. Drawing on the experience of twenty contributing researchers, the book employs dimensional analysis as a unified scientific approach to quantify similar processes on different scales.

Download Link:

Identification and Determination of Impurities in Drugs

Impurity profiling is the common name of a group of analytical activities, the aim of which is the detection, identification/structure elucidation and quantitative determination of organic and inorganic impurities, as well as residual solvents in bulk drugs and pharmaceutical formulations. Since this is the best way to characterise the quality and stability of bulk drugs and pharmaceutical formulations, this is the core activity in modern drug analysis.

Due to the very rapid development of the analytical methodologies available for this purpose and the similarly rapid increase of the demands as regards the purity of drugs it is an important task to give a summary of the problems and the various possibilities offered by modern analytical chemistry for their solution. That is the aim of this book.

The book is methodology-oriented. In the first chapter some important aspects of the background of impurity-related analytical studies (toxicological, pharmacopoeial aspects, the characterisation of the sources of impurities and the role of impurity profiling in various fields of drug research, production and therapeutic use) are summarised. Chapter two deals with related organic impurities, the strategies for impurity profiling, the use of chromatographic and related separation methods, spectroscopic, and hyphenated techniques. The subject of the third chapter is the identification and determination of residual solvents. The determination of inorganic impurities is discussed in chapter four. The special problems of degradation products as impurities are dealt with in chapter five. A separate chapter has been compiled to deal with one of the most up-to-date problems in contemporary pharmaceutical analysis, the estimation of enantiomeric purity of chiral drugs. Chapter seven is devoted to various approaches to solve the problem of polymorphic modifications as impurities. Since in the broader sense of the word the microbiological purity of drugs and drug products also belongs to this circle, the most important information from this field is summarised in chapter eight. After the mainly methodology-oriented chapters, the final one concentrates on four groups of drugs (peptides, biotechnological products, antibiotics and steroids) in order to demonstrate the use of the methods described earlier.

Download Link:

Amino Group Chemistry: From Synthesis to the Life Sciences

Here, probably the most important functional group in organic chemistry is discussed in one handy volume. The monograph covers its application -- from natural products to synthetic pharmaceuticals -- detailing complex syntheses using the amino group as templates and modern techniques focussing on the introduction of the amino group. A definitive must-have for every chemist.