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Showing posts with label Nenoscience. Show all posts
Showing posts with label Nenoscience. Show all posts

Nanotherapeutics: Drug Delivery Concepts in Nanoscience

An important and exciting aspect in the newly developing field of nanomedicine is the use of nanoparticle drug delivery systems allowing for innovative therapeutic approaches. Due to their small size, these drug delivery systems are promising tools in therapeutic approaches such as selective or targeted drug delivery towards a specific tissue or organ, enhanced drug transport across biological barriers, and intracellular drug delivery.

This timely book provides an overview of possible therapeutic applications. The first part of the book highlights general properties of and phenomena observed with nanoparticles, and the subsequent consequences for applications in drug delivery. The second part focuses on the therapeutic approaches that are possible through the use of nanoparticles, with each chapter discussing a specific disease (e.g. diabetes, cancer, inflammation, etc.) and the relevant therapeutic approaches based on the design of nanoparticulate drug delivery systems. Written in a concise manner, readers will gain an insight into the basics of nanoparticle preparation as well as a more detailed account of what is therapeutically feasible by using nanoparticle approaches.

Contents: General Aspects of Nanotherapeutics: Nanocarriers in Drug Delivery - Design, Manufacture and Physicochemical Properties (C Schmidt & A Lamprecht); Transport Across Biological Barriers (N Nafee et al.); Targeting Approaches (S Cammas-Marion); Disease-Related Approaches by Nanotherapeutics: Nanoscale Cancer Therapeutics (Y Pellequer & A Lamprecht); Nanotherapeutics for Skin Diseases (N Atrux-Tallau et al.); Nanoparticles for Oral Vaccination (J M Irache et al.); Nanoparticles: Therapeutic Approaches for Bacterial Diseases (B Moulari); Nanoparticle Therapy in Parasites Diseases: Possibility and Reality! (M Larabi); Nanocarriers in the Therapy of Inflammatory Disease (A Lamprecht).

Hansen Solubility Parameters: A User's Handbook, Second Edition

Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including polymers, inorganic salts, and biological materials.

To update his groundbreaking handbook with the latest advances and perspectives, Charles M. Hansen has invited five renowned experts to share their work, theories, and practical applications involving HSPs. New discussions include a new statistical thermodynamics approach for confirming existing HSPs and how they fit into other thermodynamic theories for polymer solutions. Entirely new chapters examine the prediction of environmental stress cracking as well as absorption and diffusion in polymers. Highlighting recent findings on interactions with DNA, the treatment of biological materials also includesskin tissue, proteins, natural fibers, and cholesterol. The book also covers the latest applications of HSPs, such as ozone-safe “designer” solvents, protective clothing, drug delivery systems, and petroleum applications.

Presenting a comprehensive survey of the theoretical and practical aspects of HSPs, Hansen Solubility Parameters, Second Edition concludes with a detailed discussion on the necessary research, future directions, and potential applications for which HSPs can provide a useful means of prediction in areas such as biological materials, controlled release applications, nanotechnology, and self-assembly.

Nanotechnology for Cancer Therapy

Encouraging communication between clinical investigators and nanoscientists, Nanotechnology for Cancer Therapy focuses specifically on effective and promising nanoscience and nanotechnology strategies for imaging and treating cancer. Among the various approaches considered, nanotechnology offers the best promise for the targeted delivery of drugs and genes to a tumor site and for alleviating side effects of chemotherapeutic agents. Renowned industrial and academic researchers describe the advantages of nanoparticles as sensing, delivery, image enhancement agents for cancer treatments, and various types of useful nanoparticles such as polymeric nanoparticles and dendrimers.

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Nanoparticulate Drug Delivery Systems

Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. This expertly written guide addresses the scientific methodologies, formulation, processing, applications, recent trends, and emerging technologies in the research of nanoparticulate drug delivery systems (NPDDS). It extensively covers applications of NPDDS, including lipid nanoparticles for dermal applications, nanocarriers for the treatment of restenosis, ocular, central nervous system, and gastrointestinal applications, and use as an adjuvant for vaccine development.

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Aerosols Handbook: Measurement, Dosimetry, and Health Effects

As more attention is dedicated to understanding the occupational health risks associated with the industrial manufacture and use of nanotechnology, Aerosols Handbook: Measurement, Dosimetry, and Health Effects is a timely presentation of the latest research in the field of aerosol science. The book covers a multitude of topics on indoor, outdoor, and industrial aerosols, including aerosol measurement, deposition, particle size distribution, and biokinetic processes. Where harmful exposure to ultrafine particles may occur through inhalation, dermal contact, and ingestion, this book discusses how the size, shape, and chemical properties of particles affect aerosol deposition in the lungs, possibly other organs, and the overall toxicity. The book covers all relevant aspects of aerosols, from epidemiology to molecular biology, and emphasizes the importance of accurate aerosol measurement. The authors discuss Chernobyl accident and miners' lungs in detail to illustrate the effects of radioactive aerosols. The final section focuses on the health effects of specific aerosols, such as diesel aerosols and ultrafine particles. By converging research from both radioactive and non-radioactive aerosols, the editors give the book a unique and more complete perspective of how aerosols behave in the lungs. Aerosols Handbook: Measurement, Dosimetry, and Health Effects is an essential resource for those who study exposure, dosages, and toxicity to develop treatments for exposure, reduce air pollution, and establish better safety regulations, particularly in industries using nanotechnologies.

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Antisense Drug Technology: Principles, Strategies, and Applications

This state-of-the-art reference provides comprehensive coverage of the development of antisense oligonucleotides to inhibit cancer cells as well as those involved in infectious, inflammatory, and immune-mediated diseases-highlighting new tools and technologies in medicinal chemistry, RNA biochemistry, and molecular and cellular biology to produce new therapeutic compounds. Presents previously unpublished data on the use of antisense technology to dissect pharmacological processes and confirm the roles of various genes! Showcasing the benefits of antisense drug use, including reduced toxicity and earlier disease detection, Antisense Drug Technology discusses · novel formulations of antisense drugs · practical methods to design effective isotype selective inhibitors · molecular mechanisms of antisense drugs · mRNA as a current biological template · modern postreceptor binding mechanisms · and more! With contributions by over 60 seasoned experts in the field and containing more than 3000 helpful references, tables, drawings, and photographs, Antisense Drug Technology is an illuminating source for organic, medicinal, and pharmaceutical chemists; biochemists; geneticists; hematologists; oncologists; molecular and cell biologists; virologists; immunologists; and medical school and graduate students in these disciplines.

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Dekker Encyclopedia of Nanoscience and Nanotechnology - 5 Volume Set

Placing specialists at the forefront of the nanoscience revolution, this reference identifies current challenges and development paths sure to influence fields ranging from materials and surface science, chemistry, and biomedicine to computer technology, information processing, and mechanical, optical, and electrical engineering-examining the design, application, and utilization of devices, techniques, and technologies critical to research at atomic, molecular, and macromolecular levels ranging from 1-100 nanometers.

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http://rapidshare.com/files/117703166/encyclo_nanosc_tech.part1.rar

http://rapidshare.com/files/117708177/encyclo_nanosc_tech.part2.rar