Rules of Thumb for Mechanical Engineers

Save time with this collection of straightforward, common-sense techniques that provide quick, accurate solutions to your engineering problems. 

Rules of Thumb for Mechanical Engineers assembles hundreds of shortcuts, calculations, practical "how-to" methods, and concise background reviews into one convenient volume. 

Whether you're concerned with design, selection, or performance, you'll find fast, accurate answers here - all without wading through pages of theory. 

Experts from all engineering disciplines have packed this book's sixteen chapters with design criteria and practical tips. You'll find easy-to-read descriptions on fluids, heat transfer, thermodynamics, seals, pumps, and compressors, drivers, gears, and bearings, as well as piping and pressure vessels. 

Also covers tribology, vibrations, materials, stress and fatigue, instrumentation, and engineering economics. 

* Save time with this collection of straightforward, common-sense techniques that provide quick, accurate solutions to your engineering problems. 

* Hundreds of shortcuts, calculations and practical "how-to" methods in one convenient volume. 

* Fast, accurate answers to design, selection, or performance issues.

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Pharmaceutical Packaging Handbook

A complete overview of the role that packaging plays in the development and delivery of pharmaceuticals and medical devices. Including a thorough examination of the industry in size and scope, this source gives an introduction drug dosage forms, vaccines, biologically produced products, and medical foods to the reader.

Pharmaceutical Packaging Handbook is the most complete and straightforward text on the market today and also lists information in an easy to follow fashion, making it a complete stand-alone reference for anyone working in the pharmaceutical industry.

discusses how packaging is designed and integrated into the product development cycle has an overview of the regulatory environment procedures provides the reader with a basic introduction into key aspects of navigating the regulations describing the materials used to package pharmaceuticals, including glass, metal, plastics, flexible films, rubbers and elastomers comments on some new hybrids used for packaging, with a short introduction to plastics, their makeup, and typical uses in packaging explores the processing techniques used with the materials to produce pharmaceutical containers and some of the strengths and weaknesses of the processes used for container fabrication introduces the reader to retort, aseptic, gas, and radiation sterilization of product discusses labeling and design for pharmaceuticals including how labels are produced, materials used, and production techniques.

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Food Plant Design

Although chemical engineering and food technology are subject areas closely related to food processing systems and food plant design, coverage of the design of food plants is often sporadic and inadequately addressed in food technology and engineering books.

Some books have attempted to treat food engineering from this dual point of view but, most have not achieved balanced coverage of the two. Focusing on food processing, rather than chemical plants, Food Plant Design presents precise design details with photos and drawings of different types of food processing plants, including food processing systems, refrigeration and steam systems, conveying systems, and buildings. The authors discuss the subject in an ordered format that gives you the tools to produce food products with minimum cost.

Including modeling procedures for food processing systems and auxiliary systems, they elucidate synthesis techniques and procedures. Using a clear structure for different levels of information and data on different food processing alternatives, the book outlines solutions to plant design problems in the context of overall optimization of an agro-industrial system and corresponding food chain.

It provides the work procedures and techniques for solving the design problems of a food processing plant and in making a defined food product.

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Handbook of Pharmaceutical Salts : Properties, Selection, and Use

An estimated half of all drug molecules used in medicine are administered as salts, and the formation and the selection of a suitable salt for a drug candidate is recognized as an essential step in the preclinical phase of modern drug development. Surprisingly, however, the scientific literature on this topic is rather limited and scattered throughout numerous journals and patents. The majority of medicinal chemists in pharmaceutical industry whose primary focus is the design and synthesis of novel compounds as future drug entities are organic chemists for whom salt formation is often a marginal activity restricted to the short-term objective of obtaining crystalline material.

Because a comprehensive resource that addresses the preparation, selection, and use of pharmaceutically active salts has not been available, researchers may forego the opportunities for increased efficacy and improved drug delivery provided by selection of an optimal salt. To fill this gap in the pharmaceutical bibliography, we have gathered an international team of seventeen authors from academia and pharmaceutical industry who, in their contributions to this volume, present the necessary theoretical foundations as well as a wealth of detailed practical experience in the choice of pharmaceutically active salts. An introductory chapter presents a concise review of the various objectives in the pursuit of pharmaceutically active salts, followed by contributions that present the theoretical background of salt formation: dissociation and ionic equilibria, solubility and dissolution (Chapters 1 and 2), evaluation of solid-state properties (Chapter 3), and safety, biopharmaceutical, and pharmaceutical-technological aspects (Chapters 4 and 5).

In Chapters 6, 7, and 8, the practice of salt formation in an industrial research-and-development environment is described, including salt-selection strategies, aspects of large-scale industrial salt production, and the significance of salt formation in industrial processing. Regulatory and patent issues are addressed in Chapters 9 and 10, and Chapter 11 provides practical examples of preparation of salts for the practitioners at the lab bench. The book concludes with a comprehensive annotated compilation of the individual salt-forming acids and bases with their relevant properties (Chapter 12), followed by an Appendix containing tables with the acids and bases sorted alphabetically and by pKa, supplemented with other useful facts and data.

The editors have taken care to address every conceivable aspect of the preparation of pharmaceutical salts. Altogether, the contributions reflect the multidisciplinary nature of the science involved in selection of suitable salt forms for new drug products. This book is destined to be an essential reference resource for students of medicinal and pharmaceutical chemistry, and an indispensable handbook for research-and-development chemists, analytical chemists, biologists, development pharmacists, regulatory and patent specialists, and medicinal scientists engaged in preclinical development of drugs.

This comprehensive up-to-date guide and information source will be an instructive companion for all scientists involved in research and development of drugs and, in particular, of pharmaceutical dosage forms.

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HVAC Troubleshooting Guide

Applicable to residential, commercial, and industrial jobs, this essential handbook puts a wealth of real-world information at your fingertips. HVAC Troubleshooting Guide shows you how to read, interpret, and prepare schedules, mechanical plans, and electrical schematics.

This handy resource will aid you in your everyday tasks and keep you up to date with the latest facts, figures, and devices. The book includes numerous illustrations, tables, and charts, troubleshooting tips, safety precautions, resource directories, and a glossary of terms.

HVAC Troubleshooting Guide helps you:

Identify and safely use tools and equipment (both new and old)
Use heat pumps and hot air furnaces
Calculate ventilation requirements
Work with refrigeration equipment and the new refrigerants
Utilize control devices, including solenoids and relays
Operate, select, and repair electric motors
Work with condensers, compressors, and evaporators
Monitor the flow of refrigerant with valves, tubing, and filters
Comply with the Section 608 refrigerant recycling rule
Program thermostats
Insulate with batts, sheet, tubing covers, and foam
Work with solid-state controls

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Dictionary of Pharmaceutical Medicine

The dictionary contains various terms typically used in pharmaceutical medicine. The 2nd edition reflects the increasing importance of this science and the changing regulatory environment in particular on research and development of new therapies as well as on the conduct of clinical trials, marketing authorisation of new medicinal products and safety aspects including pharmacovigilance."

"The number of key words has been considerably enlarged and increased to over 1,600 terms; it includes new scientific areas such as gene therapy and proteomics. Furthermore, given the importance of the internet, the new edition contains a list of most important web sites. Similar to the 1st edition, also the book explains about 1,000 abbreviations most commonly used inpharmaceutical medicine."

"This book will be a valuable tool for professionals in the area of the pharmaceutical industry, medical and pre-clinical research, regulatory affairs, marketing and marketing authorisation of pharmaceuticals.

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Pharmaceutical Preformulation and Formulation: A Practical Guide from Candidate Drug Selection to Commercial Dosage Form

Written by a panel of experts, this book covers every stage of drug development, from candidate drug selection to commercial formulation. It provides practical reference and pragmatic guide on what studies need to be undertaken, for what reasons, and at what key stages of the drug development process.

Going beyond coverage of preformulation, the book discusses biopharmaceuticals, drug delivery, formulation, and process development aspects of product development. The contributing authors share their experience and expertise in significant chapters divided into three useful sections: Aiding Candidate Drug Selection, Early Drug Development, and From Product Design to Commercial Dosage Form.

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