Pharmaceutical Coating Technology

This book is the definitive work on the theory and practice of pharmaceutical tablet and pellet coating. It describes both the practical and theoretical aspects of tablet coating, including the equipment and methods used in laboratory development, scale-up and production systems, as well as automation and validation. This book also discusses the problems of conforming to world-wide regulations, and the hazards of environmental pollution.

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http://rapidshare.com/files/125535590/Pharm_coat_tech.zip

Controlled Environments May 2008

Controlled Environments - a monthly magazine focused on clean room requirements for aspectic/sterile pharmaceutical & microelectronics manufacturing detailing latest developments in the technology, vista on the scientific background and much more.

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http://rapidshare.com/files/125318636/Cont_envir58.zip

Standardizing Medication Labels

Medications are an important component of health care, but each year their misuse results in over a million adverse drug events that lead to office and emergency room visits as well as hospitalizations and, in some cases, death. As a patient's most tangible source of information about what drug has been prescribed and how that drug is to be taken, the label on a container of prescription medication is a crucial line of defense against such medication safety problems, yet almost half of all patients misunderstand label instructions about how to take their medicines. Standardizing Medication Labels: Confusing Patients Less is the summary of a workshop, held in Washington, D.C. on October 12, 2007, that was organized to examine what is known about how medication container labeling affects patient safety and to discuss approaches to addressing identified problems.

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http://rapidshare.com/files/124853017/Stand_med_lab.zip

Oral Drug Absorption: Prediction and Assessment

A practical, hands-on guide for successfully developing oral drug products, this comprehensive reference runs the gamut from theoretical stages of computer-based calculations to practical guidelines for establishing in vitro/in vivo correlations. Coverage details the interrelationship between the physiology of the gastrointestinal tract and oral drug formulations and absorption, and progresses to the latest applications of pharmacokinetic analysis. Includes chapters by the innovators of the Biopharmaceutical Classification Scheme (BCS), human perfusions, and biorelevant dissolution testing! With over 600 literature references, equations, drawings, and photographs, Oral Drug Absorption · offers multiple methods for predicting permeability, solubility, and dissolution for oral bioavailability and bioequivalence · facilitates selection of appropriate drug candidates for development · fully elaborates on the experimental and data analysis techniques of in vitro/in vivo correlations · provides guidance to the Federal Drug Administration's BCS and its applications · appends helpful case studies to the concepts discussed · and much more! Contributions by more than 20 international specialists on the latest research make Oral Drug Absorption an invaluable tool and useful reference in the hands of pharmaceutical scientists, medicinal chemists, pharmacists, pharmacologists, toxicologists, biochemists, gastroenterologists, regulatory personnel, and graduate school students in these disciplines.

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http://rapidshare.com/files/123754625/Oraldrug_absor_preass.zip

Absorption and Drug Development: Solubility, Permeability, and Charge State

Many times drugs work fine when tested outside the body, but when they are tested in the body they fail. One of the major reasons a drug fails is that it cannot be absorb by the body in a way to have the effect it was intended to have. Permeability, Solubility, Dissolution, and Charged State of Ionizable Molecules:

• Helps drug discovery professionals to eliminate poorly absorbable molecules early in the drug discovery process, which can save drug companies millions of dollars.
• Extensive tabulations, in appendix format, of properties and structures of about 200 standard drug molecules.

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http://rapidshare.com/files/123750940/Abso_drg_dev.zip

Liquid Filtration

This book is a state-of-the-art review of liquid filtration in the chemical process and allied industries. Interpretations of the phenomenological observations of the hydrodynamics of filtration are given in the hopes of establishing more theoretical and generalized bases of design methodology. Specific design and selection criteria are reviewed, and typical industrial problems and their solutions are presented.

Liquid Filtration is a fundamental unit operation extensively practiced throughout the chemical process, petroleum, and allied industries. It involves the separation, removal, and collection of a discrete phase of matter existing in a dispersed or colloidal state in suspension. This separation is most often performed in the presence of a complex media structure in which physical, physiochemical and/or electrokinetic forces interact.

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http://rapidshare.com/files/123744554/Liq__filt_2Ed.zip

Cellular Drug Delivery: Principles and Practice

An authoritative and up-to-date survey of the fundamental principles, and practice of drug delivery at the cellular level. On the principles side, the authors discuss the broad spectrum of cellular delivery, ranging from coverage of cell-mediated immunity, gene delivery, and protein targeting, to cellular drug transport, cellular drug permeability, and a variety of carrier system related to targeted drug delivery. On the practice side, the authors focus on technological developments in cellular drug delivery, including novel formulations for the delivery of DNA and antisense oligonucleotides ,as well as drug targeting with immunoglobulin formulations and antibody-mediated approaches.

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http://rapidshare.com/files/123260862/Cell_drg_dly.zip